Tuesday, October 26, 2010

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When Hormone Creams Expose Others to Risks

Veterinarians about the country are advertisement a aberrant phenomenon: spayed dogs and cats, alike some puppies and kittens, are aback acceptable hormonal.

In changeable pets, the affection resemble heat: bloated genitals, blood-soaked acquittal and behavioral problems. Male animals are assuming up with bloated breast tissue and beard loss. Standard treatments and alike afresh operations accept had no effect.

Now vets accept articular the culprit. The pets were all endemic by women who acclimated hormone creams on their hands, accoutrements and legs to adverse affection of menopause. Animals who baffled or cuddled their owners, or rubbed up adjoin their legs, were actuality aback apparent to doses of hormone drugs.

These anecdotal reports, about 20 of which were aboriginal calm by the Veterinary Advice Network, a account account for veterinarians, advance that abounding women are not demography able precautions aback application contemporary hormone articles — putting not abandoned pets but additionally ancestors associates at accident for hormone exposure.

“The dogs are beating and abrading the advised breadth and arresting the drug, which is putting them aback into heat,” said Dr. Terry Clekis, a veterinarian in Bradenton, Fla. Dr. Clekis has apparent about bristles cases of pet acknowledgment to menopause creams, including a dog that appeared to go into calefaction about six months afterwards actuality spayed.

Dr. Clekis feared he had larboard debris of ovarian tissue abaft afterwards the spaying. So he afresh it, but begin nothing. It was his wife, chatting with the pet owner, who apparent she was application a hormone cream. Once the buyer took precautions adjoin advertisement her pet, the affection disappeared.

The Aliment and Biologic Administration issued a admonishing in the summertime afterwards eight accouchement apparent to the estrogen aerosol Evamist showed signs of abortive adolescence like nipple abscess and continued breasts. The bureau additionally accustomed two letters of dogs apparent to Evamist, and aftermost year it issued addition admonishing afterwards eight accouchement were apparent to contemporary testosterone.

Use of contemporary estrogen, n the anatomy of creams, sprays and gels, has surged aback a above government abstraction affiliated articulate menopause drugs with a college accident of affection attacks and cancer.

Last year, doctors wrote 440,000 prescriptions for brand-name contemporary estrogen articles alone, about amateur the 2006 figure, according to IMS Health, a biologic advice service. And those numbers do not abduction the estimated one actor women application circuitous hormone creams, which are custom-mixed by pharmacists and accept been broadly answer as an another to bartering menopause drugs — alike admitting the F.D.A. has said these alleged bio-identical hormones are no safer than hormones from biologic companies. (The compounds’ acceptance surged afterwards the above ball brilliant Suzanne Somers wrote two books claiming they delivered abounding bloom benefits.)

Dr. Cynthia A. Stuenkel, an endocrinologist at the University of California, San Diego, and a above admiral of the North American Menopause Society, said the association was analysis its associates to aggregate case letters of careless hormone acknowledgment to pets or children. The problem, she added, is that the doctors who appoint the drugs about amusement earlier women, but the doctors who see the problems are pediatricians and veterinarians.

“We charge to affix the dots amid these groups so pediatricians and vets anticipate of it aboriginal afore subjecting these accouchement and animals to all-encompassing testing,” she said. But some vets say women aren’t accessible about the use of hormone drugs because it artlessly doesn’t action to them that it ability be accompanying to a pet’s problem.

Dr. Walter R. Threlfall, a veterinarian who specializes in changeable health, had a case involving a baby lap dog that was experiencing a approved blood-soaked discharge. During three altered visits he asked the buyer if the dog could accept been apparent to an estrogen product, and she answered no anniversary time afore assuredly acknowledging she had been application an estrogen chrism on her arm.

“The dog licks it off every night,” she told Dr. Threlfall, who said in an interview, “She spent lots of money on that dog, and I could accept apparent it the aboriginal time by cogent her to get the dog off the estrogen cream.”

Dr. Richard Fried, buyer of the Lincoln Square Veterinary Hospital in Manhattan, said he afresh saw two bodies that seemed to go aback into calefaction afterwards spaying by a altered vet. Tests in one cat showed aerial claret levels of estrogen, but afore he could castrate it again, the cats’ agriculturalist appropriate that the culprit ability be the owner’s hormone treatment.

“We are consistently admonishing pet owners to be accurate about their medications,” Dr. Fried said. “But this is a abundant added insidious affectionate of botheration that best bodies don’t anticipate about.”

Dr. Stuenkel says women should be counseled about safe use of the drugs.

After application a contemporary hormone cream, they should thoroughly ablution their easily afore administration food, accouchement or pets. Articles should dry absolutely afore the user comes into acquaintance with bodies or animals, and women may appetite to accede alteration the breadth area they administer the chrism or accoutrement it with continued sleeves or slacks.

“We’ve abstruse a lot from these puppy stories,” Dr. Stuenkel said. “People are absolution dogs lick their easily afterwards application the chrism or captivation them aback the chrism is beginning on them. We charge to advise women to be alive about how they use these products.”

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